IS EXPLORATION OF ALTERNATE IMMUNE PATHWAYS NEEDED IN HIDRADENITIS SUPPURATIVA? A CASE OF ATOPIC DERMATITIS AND CONCURRENT HIDRADENITIS SUPPURATIVA RESPONDING TO DUPILUMAB

Hidradenitis suppurativa (HS) is an inflammatory dermatosis associated with overactive T helper 1/T helper 17 (Th1/Th17) cells.HS has been effectively treated with biologic medications; however, many such biologics lack large randomized controlled trials.Only one such biologic, adalimumab, has been approved by the US Food and Drug Administration (F

Previous work demonstrates that the hearing loss in Alport mice is caused by defects in the stria vascularis.As the animals age, progressive thickening of strial capillary basement membranes (SCBMs) occurs associated with elevated levels of extracellular matrix expression and hypoxia-related gene and protein expression.These conditions render the a

The socio-economic context is constantly challenging traditional employment relationships while new forms of employment are emerging, with acute risk of precarity for workers.In Europe, some non-standard workers find collective iphone 14 price chicago action as a valid alternative to the isolation and experiment solidarity and access to social secu

Opatroides punctulatus Brullé, 1832 is a detritivore tenebrionid beetle native to the Old World that was detected in the United States over 20 stickers logos dallas cowboys years ago.It is well adapted to Mediterranean climates between 30°N and 45°N, characterized by hot, dry summers and cool, wet winters.We confirm iphon